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SG Diagnostics

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COVID-19 vaccine efficacy and effectiveness

COVID-19 vaccine efficacy and effectiveness Approximately 96 COVID-19 vaccines are at various stages of clinical development.1 At present, we have the interim results of four studies published in scientific journals (on the Pfizer–BioNTech BNT162b2 mRNA vaccine,2 the Moderna–US National Institutes of Health [NIH] mRNA-1273 vaccine,3 the AstraZeneca–Oxford ChAdOx1 nCov-19 vaccine,4 and the Gamaleya GamCovidVac [Sputnik …

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Effectiveness of Covid-19 Vaccines against the B.1.617.2 (Delta) Variant

Effectiveness of Covid-19 Vaccines against the B.1.617.2 (Delta) Variant Abstract BACKGROUND The B.1.617.2 (delta) variant of the severe a cute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes coronavirus disease 2019 (Covid-19), has contributed to a surge in cases in India and has now been detected across the globe, including a notable increase in …

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Self-testing with antigen tests as a method for reduction SARS-CoV-2

Self-testing with antigen tests as a method for reduction SARS-CoV-2 In the COVID-19 pandemic, the provision of adequate health care to patients is fundamental to keep mortality low. Medical stuff, in particular emergency medical service personnel, who represent the first line of the fight against COVID-19 [1]. It is in the pre-hospital set-ting that each …

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A Crystal Structure of the Dengue Virus NS5

A Crystal Structure of the Dengue Virus NS5 Protein Reveals a Novel Inter-domain Interface Essential for Protein Flexibility and Virus Replication Abstract Flavivirus RNA replication occurs within a replication complex (RC) that assembles on ER membranes and comprises both non-structural (NS) viral proteins and host cofactors. As the largest protein component within the flavivirus RC, …

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